Cannabidiol (CBD) entered the market in a vast way after stopping an epileptic seizure in the United States of America. Many medical researchers have found this organic compound to be highly effective in treating several health conditions, including spasms, chronic pain, anxiety, depression, and many more. But what exactly is cannabis? How different is it from THC? This article will help you understand everything about CBD oil.
What is CBD?
Cannabidiol (often abbreviated as CBD) is the main chemical compound found in the marijuana plant. Unlike tetrahydrocannabinol (THC), which is the most popular constituent, CBD is entirely non-psychoactive. With organic compound, don’t expect to get “high”. CBD is all about relaxation, ‘not intoxication.
Whilst cannabinoids may still have a slight effect on the human body, consuming CBD alone isn’t going to make you feel high like the way THC does. For many years, medical professionals, as well as the general public, disregarded CBD because its psychoactive counterpart (THC) took center stage.CBD oil for Dogs is another great product.
Now, CBD oil’s medical potential has taken the world by storm. Clinical studies have established that CBD shows great potential as an anti-inflammatory, analgesic, antioxidant, anti-psychotic, neuroprotectant, anti-tumoral agent, and anxiolytic. Most patients usually used CBD as an oil. Those with chronic conditions like cancer, multiple sclerosis, and epilepsy can also use medical marijuana to treat their symptoms.
CBD oil: How Does It Actually Work?
Being one of the 80 chemical compounds found in the marijuana plant, CBD is usually described as an agonist that binds itself to special receptors in the human body, called cannabinoid receptors. Some of these receptors are predominant in the CNS (central nervous system) whilst others are spread in almost every body organ. Certain CBD receptors are even present in the skin, reproductive system, and the digestive tract.bb
By taking cannabis, you’re consuming agonists which interact with various cannabinoid receptors found in your body cells. Together, these two types of cell receptors form a vast endocannabinoid system (ECS). And this ECS can be described as a large network of cell receptors which perform numerous functions. It helps in almost everything, including mood, motor control, reproduction, memory, immune function, sleep, pain reception, appetite, and bone development. In short, CBD creates optimal energy balance in your body, producing its therapeutic effects. Cannabinoids are able to interact with human body cells because it has a chemical composition that’s similar to the ones produced naturally by the body, called endocannabinoids.
As mentioned earlier, THC is psychoactive but CBD isn’t. Though both compounds are cannabinoids, each of them interacts with the body differently. THC directly interacts with the CB1 (cannabinoid receptor 1), which is highly concentrated in the CNS.
Cannabinoid, however, does not interact with the body’s CB1 in the same way. Unlike THC, which binds to what’s referred to as the orthosteric site, CBD binds on what’s referred to as an allosteric site. This is what enables this organic product to modulate THC’s psychoactivity.
CBD Oil: How else does it work?
CBD has a lot of effects on the human body. It’s known to have a direct or an indirect effect on the following: serotonin receptors (essential for mood as well as stress management), vanilloid receptors (responsible for pain modulation), and adenosine receptors (essential for the sleep-wake pattern).
Certain rodent studies have found that CBD can also work by obstructing a particular enzyme called fatty-acid amide hydrolase (FAAH), whose function is to break down the endocannabinoid anandamide that occurs naturally in the human body. This molecule plays an important role in regulating basic functions such as pleasure, memory, pain, ovulation, and sleep.
According to recent medical studies, CBD doesn’t block FAAH (fatty-acid amide hydrolase) in humans. Instead, it engages proteins which are responsible for binding anandamide to FAAH, and not to fatty-acid amide hydrolase itself.
CBD Oil: Conditions it can treat
Furthermore, it is important to remember that there are a few different types of cannabinoids, and these all have a slightly different impact on the user. For instance, Delta-8 is a cannabis compound that is widely used because of its similarity to THC, the main compound in cannabis that gets you high and causes euphoria, happiness, sedation, symptom relief, and more. If you would like to learn more about Delta-8, you can take a look at some reviews of delta 8 brands online.
Though THC is believed to cause paranoia, cannabinoid is a great option for those who don’t want that psychoactive experience.
According to recent research publications, cannabinoid can effectively ease social anxiety.
Understanding the “whole plant medicine” push
Of course, CBD is considered a powerful medication on its own. However, combining the compound with other cannabinoids tends to amplify its side effects. A big debate surrounding CBD is centered on pushing towards “whole plant medicine.” And, the idea behind the push (i.e. the whole plant medicine) is heavily linked to the entourage effect.
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According to the proponents, the entourage effect can be achieved by combining cannabinoids, such as CBD and THC, to produce therapeutic effects that can hugely benefit the body. This explains why certain epileptic sufferers respond positively to CBD, while others exhibit a better response to THC. Pharmaceutical medicines have already used the entourage effect. For instance, a Multiple Sclerosis drug known as Sativex by GW Pharmaceuticals features a THC-CBD balanced ratio. The combination works better to manage multiple sclerosis symptoms as opposed to just using CBD alone.
Solution to Opioids Crisis
CBD oil could be a promising alternative to the Opioid-based products Crisis. According to recent research publications, the introduction of CBD-based products has already seen a 25 percent drop in deaths caused by opioid overdose. Additionally, patients with pain-related problems using medicinal cannabis (which is high in CBD) consumed 64 percent fewer opioid painkillers.
A Sedation or Energizing Agent
When taken in larger doses (larger than 100 milligrams), CBD oil-based products can be used to sedate. Thus, it can help insomniacs as well as other individuals with sleep problems. Plus, in lesser doses, CBD oil products can make one more alert.
